306
Chapter 7
1000
100
10
1
'a
Figure 7.22 The morphology of
G. candidum
during the outgrowth of a single spore. Measurements of
the total hyphal length (/,) in ^m, the number of tips, and the hyphal growth unit length (/hBU
) in Mm per
tip are compared with model simulations (lines). The data are taken from Trinci (1974) and model
simulations are from Nielsen (1993).
PROBLEMS
Problem 7.1 Estimation of parameters in the Monod model
From measurements of the residual glucose concentration in a steady-state chemostat at various dilution
rates, you can find the following results:
ZH h[)
s
(me L
0.13
11
0.19
14
0.23
18
0.36
38
0.67
85
0.73
513
Calculate by linear regression the parameters in the Monod model.
You want to check the value of
determined above and therefore increase the dilution rate in the
chemostat to
D =
1.1 h'1. This results in a rapid increase in the glucose concentration, and after a while
s ยป
Kv
The result of the change in dilution rate is a decrease in the biomass concentration, and during the
washout you measure the biomass concentration as a function of time, and obtain the following results:
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