Index
521
uncoupling agents 18-22,264
Cell wall 13, 15,268,301,332
Cephalosporins 10,35-36,39
Cephalosporin C 35
Chemostat: see Bioreactor
Chi-square distribution 85
use in error identification 85-88
Chromosome 13, 15,288-289,309
duplication in yeast 294
Citric acid
degree of reduction 62
heat of combustion 104
production by
A. niger
71-72
production by
C. lipolytica
156-159
Coexistence of several organisms 397-402
of predator and prey 404-409
Colonial mutants 294
Compartment 29,61, 160,239
Compartment models
for metabolism and growth 160, 239,265-271,276-277,284
for mixing 503-504,508,511
Competition
between organisms using the same substrate 397-401
between prey and predator 404
in enzyme kinetics 195-204
Consistency analysis 67-71
Consistency index 498-499
Continuous Stirred Tank Reactor (CSTR): see Bioreactor
Contois model: see Growth rate equations
Cooperativity 201-204
Com steep liquor 40
oxygen solubility in 448
Correlated measurements 83-85, 107, 159, 199-201,334
C.
giutamicum
lysine production 76,164, 180
Coulter counter 319-321
Crabtree effect 30, 171,256-260
Cultivation
batch 246-249,341-352
fed-batch 367-371
plug flow reactor 372-379
stined tank, continuous
general mass balance 342
mixed microbial population 397-409
steady state 47-53,341,352-364
with biomass recirculation 359-364
with gas phase substrate 364-366
transient 380-409
Culture parameters 261
Culture variables 261
Cybernetic model 274-278
matching law model 277
of
K. oxytoca
278
variables 265,276
Damköhler number 458
Daughter cell: see Yeast budding
Degrees of freedom 73,81,85-86, 123, 135, 142-143,444
Deoxyribonucleic acid: see DNA
Diauxic growth 13,251,274
modeling 274,277-278,281
of
S. cerevisiae
13
Diffusion 16-18
facilitated 16,20-22
free (molecular passive) 16
into pellets 424, 456,463
of oxygen 16, 423-424,430,452,454-455
of phenoxyacetic acid 19
Diffusion coefficient 21 -22,379,428-430,452
in dimensionless groups 443
in lipid membrane 16-18
in pellets effective 460
for solutes in dilute aqueous solutions 454
relation to volumetric mass transfer coefficient 430
Dilution rate 7, 49-50
critical 50,67-71
maximum 249,273,329,354,359
Dimensionless groups related to mass transfer 442-444
aeration number 479,488-489, 504,507, 514-515
Biot number 469
Damkôhler number 458
Froude number 437,442,489, 501
Grashof number 443,445,459-460
Peclet number 443,445
Reynolds number 437,442-443
Schmidt number 443,445
Sherwood number 443,445-447
Dispersion model 379
DNA
content in
E. coti
32,39,266,288,290
content in
S. cerevisiae
39, 55, 290, 321
elemental composition 55
industrial production of 10
measurements of 32, 159,266,295,321
replication 339,281-283
technology 1-2,39,43
Duplication cycle: see Filamentous microorganism
Effectiveness factor
for reaction and film transport 458
for reaction and solid phase transport 464-468
Electron acceptor 72
anaerobic growth of
S. cerevisiae
129
Electron transport 23,28,110,129
Elemental composition 55-56,62,136
matrix 73,81,145
Elemental mass balance 68,73-74
Embden-Meyerhof-Pamas pathway 26
Energy charge 31
Enthalpy
changes of, table 104
free 95,97
of combustion 102
Error diagnosis 86-88
chi-square distribution 85
redundancy 86-87
matrix 86-87
test function 86-88
variance covariance matrix 87
E. coti
4, 14, 29-30
ash content and composition 56
ATP and NADPH requirement for biosynthesis 32, 133
ATP requirement for maintenance, biomass yield 127
diauxic growth 251,274,278-284
previous page 543 Bioreaction Engineering Principles, Second Edition  read online next page 545 Bioreaction Engineering Principles, Second Edition  read online Home Toggle text on/off